ZIP codes in Mississippi County
7 ZIPs touch Mississippi County, Missouri. The blue dashed line is the county border; orange ZIPs reach into it.
7
ZIP codes
4
cross the county line
34,462
people in these ZIPs
115
counties in MO
Most people
Mississippi County ZIP list
More counties in Missouri
- Madison County8
- Maries County10
- Marion County10
- McDonald County15
- Mercer County7
- Miller County17
- Moniteau County15
- Monroe County16
- Montgomery County12
- Morgan County16
- New Madrid County17
- Newton County17
Questions people actually ask
How many ZIP codes are in Mississippi County, Missouri?
7 ZIP codes reach into Mississippi County, including 1 PO Box or single-address ZIPs placed by the town they serve. 4 of them are only partly in the county and also cover a neighboring county.
Which ZIP code in Mississippi County has the most people?
63801 (Sikeston) has about 22,027 residents, the most of any ZIP touching Mississippi County, in the Census Bureau’s ACS 2020–2024 estimates.
Can a ZIP code be in Mississippi County and another county?
Yes. ZIP codes follow mail routes, not county lines. Rows marked with a percentage show how much of that ZIP’s land is in Mississippi County. For one address, pin the exact spot on the ZIP finder to see its county.
Where does this list come from?
ZIP areas and their county overlaps come from the Census Bureau’s 2020 ZIP Code Tabulation Area to county relationship file. PO Box ZIPs have no area, so each is placed in the county of the ZIP area nearest the town it serves.
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Updated 2026-11-10 · Where the data comes from